Dead Space 3 Sorry This Application Cannot Run Under A Virtual Machine

The error "Sorry, this application cannot run under a virtual machine" in Dead Space 3 occurs when the game's DRM (Digital Rights Management) misidentifies your physical PC as a virtual environment. This is frequently triggered by modern Windows security features like Hyper-V or Core Isolation that use virtualization at the kernel level.

Windows 10 and 11 use "Memory Integrity" to protect against attacks, but it relies on virtualization technology that Dead Space 3 detects as a VM. Go to Windows Security > Device Security. Click on Core isolation details. Toggle Memory Integrity to Off. Restart your PC. 3. Force-Disable Hypervisor via Command Prompt The error "Sorry, this application cannot run under

Open Windows Security (Defender).
Go to Device Security > Core isolation details.
Turn the Memory integrity switch to Off. Reboot.

"Sorry, This application cannot run under a Virtual Machine." Open Windows Security (Defender)

Press Windows Key + R, type msconfig, and hit Enter.
Go to the Services tab.
Check the box "Hide all Microsoft services" (Crucial step).
Click Disable all.
Go to the Startup tab and click Open Task Manager.
Disable all startup items in Task Manager.
Close Task Manager and click OK in the System Configuration window.
Restart your computer.
Try launching the game.
Step 4: Disable Virtual Machine Platform. "Sorry, This application cannot run under a Virtual Machine